Edward A. Sausville: search on Z-Library

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1

Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents

Brian K. Adams, Eva M. Ferstl, Matthew C. Davis, Marike Herold, Serdar Kurtkaya, Richard F. Camalier, Melinda G. Hollingshead, Gurmeet Kaur, Edward A. Sausville, Frederick R. Rickles, James P. Snyder,

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 508 KB

english, 2004

2

Clinical Development of 17-Allylamino, 17-Demethoxygeldanamycin

Sausville, Edward, Tomaszewski, Joseph, Ivy, Percy

Journal:

Current Cancer Drug Targets

Year:

2003

Language:

english

File:

PDF, 91 KB

english, 2003

3

Natural Products and Derivatives as Leads to Cell Cycle Pathway Targets in Cancer Chemotherapy

Newman, David, Cragg, Gordon, Holbeck, Susan, Sausville, Edward

Journal:

Current Cancer Drug Targets

Year:

2002

Language:

english

File:

PDF, 260 KB

english, 2002

4

S IGNAL T RANSDUCTION –D IRECTED C ANCER T REATMENTS *

Sausville, Edward A., Elsayed, Yusri, Monga, Manish, Kim, George

Journal:

Annual Review of Pharmacology

Year:

2003

Language:

english

File:

PDF, 471 KB

english, 2003

5

Expression of the hypoxia inducible factor-1alpha in head and neck squamous cell carcinoma

Ruben Cabanillas, Marta Canel, Juan Pablo Rodrigo, Maria Dolores Chiara, Carlos Suarez-Nieto, Edward A. Sausville, Carter Van Waes

Journal:

Otolaryngology - Head and Neck Surgery

Year:

2004

Language:

english

File:

PDF, 36 KB

english, 2004

6

Mining the National Cancer Institute's Tumor-Screening Database: Identification of Compounds with Similar Cellular Activities

Rabow, Alfred A., Shoemaker, Robert H., Sausville, Edward A., Covell, David G.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 1.16 MB

english, 2002

7

Paullones, a Series of Cyclin-Dependent Kinase Inhibitors: Synthesis, Evaluation of CDK1/Cyclin B Inhibition, and in Vitro Antitumor Activity

Schultz, Christiane, Link, Andreas, Leost, Maryse, Zaharevitz, Daniel W., Gussio, Rick, Sausville, Edward A., Meijer, Laurent, Kunick, Conrad

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 116 KB

english, 1999

8

Disparities in black and white patients with multiple myeloma referred for autologous hematopoietic transplantation: A single center study

Bhatnagar, Vishal, Wu, Yin, Goloubeva, Olga G., Ruehle, Kathleen T., Milliron, Todd E., Harris, Carolynn G., Rapoport, Aaron P., Yanovich, Saul, Sausville, Edward A., Baer, Maria R., Badros, Ashraf Z.

Journal:

Year:

2015

Language:

english

File:

PDF, 255 KB

english, 2015

9

State of the Art: Oncogenes, Growth Factors, and Lung Cancer

Sausville, Edward, Fisher, James

Journal:

Year:

1987

Language:

english

File:

PDF, 414 KB

english, 1987

10

A direct interaction between NQO1 and a chemotherapeutic dimeric naphthoquinone

Pidugu, Lakshmi Swarna Mukhi, Mbimba, J.C. Emmanuel, Ahmad, Muqeet, Pozharski, Edwin, Sausville, Edward A., Emadi, Ashkan, Toth, Eric A.

Journal:

BMC Structural Biology

Year:

2016

Language:

english

File:

PDF, 3.11 MB

english, 2016

11

In vitro and in vivo evaluations of the tyrosine kinase inhibitor NSC

Ioannis A. Avramis, Garyfallia Christodoulopoulos, Atsushi Suzuki, Walter E. Laug, Ignacio Gonzalez-Gomez, George McNamara, Edward A. Sausville, Vassilios I. Avramis

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2002

Language:

english

File:

PDF, 1.76 MB

english, 2002

12

Inhibition of CDKs as a Therapeutic Modality

EDWARD A. SAUSVILLE, JILL JOHNSON, MICHAEL ALLEY, DANIEL ZAHAREVITZ, ADRIAN M. SENDEROWICZ

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 3.72 MB

english, 2000

13

UCN-01 Enhances the In Vitro Toxicity of Clinical Agents in Human Tumor Cell Lines

Anne Monks, Erik D. Harris, Anne Vaigro-Wolff, Curtis D. Hose, John W. Connelly, Edward A. Sausville

Journal:

Investigational New Drugs

Year:

2000

Language:

english

File:

PDF, 202 KB

english, 2000

14

Selective Accumulation of the Endoplasmic Reticulum–Golgi Intermediate Compartment Induced by the Antitumor Drug KRN5500

Masaru Kamishohara, Susan Kenney, Renee Domergue, David T. Vistica, Edward A. Sausville

Journal:

Experimental Cell Research

Year:

2000

Language:

english

File:

PDF, 598 KB

english, 2000

15

Changes in the exposure of tryptophyl and tyrosyl residues in thrombin due to diisopropylphosphorofluoridate and benzamidine inhibitions

German B. Villanueva, C. William Batt, Edward Sausville, Victor Tortorelli, Kenneth Cubelli, William Brunner

Journal:

Biochemical and Biophysical Research Communications

Year:

1975

Language:

english

File:

PDF, 404 KB

english, 1975

16

Phase 1 dose-escalation, pharmacokinetic, and cerebrospinal fluid distribution study of TAK-285, an investigational inhibitor of EGFR and HER2

Patricia LoRusso, Karthik Venkatakrishnan, E. Gabriela Chiorean, Dennis Noe, Jing-Tao Wu, Serap Sankoh, Maria Corvez, Edward A. Sausville

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 471 KB

english, 2014

17

Phase I dose-escalation study of AZD7762, a checkpoint kinase inhibitor, in combination with gemcitabine in US patients with advanced solid tumors

Sausville, Edward, LoRusso, Patricia, Carducci, Michael, Carter, Judith, Quinn, Mary F., Malburg, Lisa, Azad, Nilofer, Cosgrove, David, Knight, Richard, Barker, Peter, Zabludoff, Sonya, Agbo, Felix, O

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2014

Language:

english

File:

PDF, 560 KB

english, 2014

18

Asparaginase in the treatment of non-ALL hematologic malignancies

Emadi, Ashkan, Zokaee, Hania, Sausville, Edward A.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2014

Language:

english

File:

PDF, 403 KB

english, 2014

19

State of the Art: Clinical Review of Lung Cancer

Sausville, Edward, Scoggin, Charles

Journal:

Year:

1987

Language:

english

File:

PDF, 396 KB

english, 1987

20

Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin

Bubb, Michael R., Senderowicz, Adrian M J, Sausville, Edward a., Duncan, Kimberly L K, Korn, Edward D.

Journal:

Journal of Biological Chemistry

Year:

1994

Language:

english

File:

PDF, 384 KB

english, 1994

21

P-D6 Lasting Reduction Of HIV Replication In Chronically Infected Humanized Mice (HSC-NSG) By Targeting Transcription With A CDK9 Inhibitor

Medina-Moreno, Sandra, Le, Nhut, Zapata, Juan, Bryant, Joseph, Sausville, Edward, Redfield, Robert, Heredia, Alonso

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2017

Language:

english

File:

PDF, 2.69 MB

english, 2017

22

Benzodithiophenes Induce Differentiation and Apoptosis in Human Leukemia Cells

Jing, Yongkui, Hellinger, Nella, Xia, Lijuan, Monks, Anne, Sausville, Edward A., Zelent, Arthur, Waxman, Samuel

Journal:

Cancer Research

Year:

2005

Language:

english

File:

PDF, 611 KB

english, 2005

23

Optimizing pegylated asparaginase use: An institutional guideline for dosing, monitoring, and management

Bade, Najeebah A, Lu, Crystal, Patzke, Ciera L, Baer, Maria R, Duong, Vu H, Law, Jennie Y, Lee, Seung T, Sausville, Edward A, Zimrin, Ann B, Duffy, Alison P, Lawson, Justin, Emadi, Ashkan

Journal:

Journal of Oncology Pharmacy Practice

Year:

2019

File:

PDF, 541 KB

2019

24

Determination of MS-275, a novel histone deacetylase inhibitor, in human plasma by liquid chromatography–electrospray mass spectrometry

Kyunghwa Hwang, Milin R Acharya, Edward A Sausville, Suoping Zhai, Eunhee W Woo, Jürgen Venitz, William D Figg, Alex Sparreboom

Journal:

Journal of Chromatography B

Year:

2004

Language:

english

File:

PDF, 100 KB

english, 2004

25

Jasplakinolide: interaction with radiation and hyperthermia in human prostate carcinoma and Lewis lung carcinoma

Hideya Takeuchi, Gulshan Ara, Edward A. Sausville, Beverly Teicher

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1998

Language:

english

File:

PDF, 289 KB

english, 1998

26

Induction of apoptosis in human leukemia cells by the tyrosine kinase inhibitor adaphostin proceeds through a RAF-1/MEK/ERK- and AKT-dependent process

Yu, Chunrong, Rahmani, Mohamed, Almenara, Jorge, Sausville, Edward A, Dent, Paul, Grant, Steven

Journal:

Year:

2003

Language:

english

File:

PDF, 511 KB

english, 2003

27

A phase I/II study of carfilzomib 2–10-min infusion in patients with advanced solid tumors

Papadopoulos, Kyriakos P., Burris, Howard A., Gordon, Michael, Lee, Peter, Sausville, Edward A., Rosen, Peter J., Patnaik, Amita, Cutler, Richard E., Wang, Zhengping, Lee, Susan, Jones, Suzanne F., In

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2013

Language:

english

File:

PDF, 491 KB

english, 2013

28

Human Small-Cell Lung Cancers Show Amplification and Expression of the N-myc Gene

Marion M. Nau, Burke J. Brooks, Desmond N. Carney, Adi F. Gazdar, James F. Battey, Edward A. Sausville and John D. Minna

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 1.11 MB

english, 1986

29

Looking for answers: the current status of neoadjuvant treatment in localized soft tissue sarcomas

Nathenson, Michael J., Sausville, Edward

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 643 KB

english, 2016

30

Relapsed Philadelphia Chromosome-Positive Pre-B-ALL after CD19-Directed CAR-T Cell Therapy Successfully Treated with Combination of Blinatumomab and Ponatinib

El Chaer, Firas, Holtzman, Noa G., Sausville, Edward A., Law, Jennie Y., Lee, Seung Tae, Duong, Vu H., Baer, Maria R. , Koka, Rima, Singh, Zeba N., Hardy, Nancy M., Emadi, Ashkan

Journal:

Acta Haematologica

Year:

2019

File:

PDF, 120 KB

2019

31

ChemInform Abstract: 2-Substituted Paullones: CDK1/Cyclin B-Inhibiting Property and in vitro Antiproliferative Activity.

Conrad Kunick, Christiane Schultz, Thomas Lemcke, Daniel W. Zaharevitz, Rick Gussio, Ravi K. Jalluri, Edward A. Sausville, Maryse Leost, Laurent Meijer

Journal:

Year:

2000

File:

PDF, 28 KB

2000

32

Experimental design and interaction analysis of combination studies of drugs with log-linear dose responses

Hong-Bin Fang, Douglas D. Ross, Edward Sausville, Ming Tan

Journal:

Statistics in Medicine

Year:

2008

Language:

english

File:

PDF, 183 KB

english, 2008

33

Geldanamycins exquisitely inhibit HGF/SF-mediated tumor cell invasion

Hay, Rick, Gustafson, Margaret, Shen, Yuehai, Wenkert, David, Woude, George F Vande, Xie, Qian, Gao, Chong-Feng, Shinomiya, Nariyoshi, Sausville, Edward

Journal:

Year:

2005

Language:

english

File:

PDF, 507 KB

english, 2005

34

Principles of Clinical Pharmacology || Drug Discovery

Sausville, Edward A.

Year:

2012

Language:

english

File:

PDF, 210 KB

english, 2012

35

Effect of chelating agents and metal ions on the degradation of DNA by bleomycin

Sausville, Edward A., Peisach, Jack, Horwitz, Susan B.

Journal:

Year:

1978

Language:

english

File:

PDF, 842 KB

english, 1978

36

ESMRMB 2013, 30th Annual Scientific Meeting, Toulouse, France, 3-5 October: Abstracts, Saturday

Papadopoulos, Kyriakos P., Burris, Howard A., Gordon, Michael, Lee, Peter, Sausville, Edward A., Rosen, Peter J., Patnaik, Amita, Cutler, Richard E., Wang, Zhengping, Lee, Susan, Jones, Suzanne F., In

Journal:

Magnetic Resonance Materials in Physics, Biology and Medicine

Year:

2013

Language:

english

File:

PDF, 6.28 MB

english, 2013

37

Unbalanced 11;18 translocation in an acute erythroid leukemia after radioactive iodine therapy

Trikalinos, Nikolaos A., Chen, Qing, Ning, Yi, Sausville, Edward A., Baer, Maria R.

Journal:

Cancer Genetics

Year:

2013

Language:

english

File:

PDF, 353 KB

english, 2013

38

Cancer Drug Design and Discovery || Heat shock protein-90 directed therapeutics and target validation

SAUSVILLE, EDWARD A.

Year:

2008

Language:

english

File:

PDF, 213 KB

english, 2008

39

Prolactin-producing pituitary carcinoma with pulmonary metastases

Daniel M. Atienza, Robert J. Vigersky, Ernest E. Lack, Marisa Carriaga, Eileen J. Rusnock, Edward Tsou, Federico Cerrone, Jorge G. Kattah, Edward A. Sausville

Journal:

Year:

1991

Language:

english

File:

PDF, 861 KB

english, 1991

40

Lymphomatoid papulosis associated with Ki-1-positive anaplastic large cell lymphoma. A report of two cases and a review of the literature

Matthew J. McCarty, Svetislava J. Vukelja, Edward A. Sausville, James J. Perry, William D. James, Elaine S. Jaffe, Raymond B. Weiss

Journal:

Year:

1994

Language:

english

File:

PDF, 3.05 MB

english, 1994

41

Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models

Victoria Smith, Edward A. Sausville, Richard F. Camalier, Heinz-Herbert Fiebig, Angelika M. Burger

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2005

Language:

english

File:

PDF, 507 KB

english, 2005

42

Treatment of catheter-related deep vein thrombosis in patients with acute leukemia with anticoagulation

Oliver, Nora, Short, Briana, Thein, Mya, Duong, Vu H., Tidwell, Michael L., Sausville, Edward A., Baer, Maria R., Kamangar, Farin, Emadi, Ashkan

Journal:

Leukemia and Lymphoma

Year:

2015

Language:

english

File:

PDF, 558 KB

english, 2015

43

The broad-range cyclin-dependent kinase inhibitor UCN-01 induces apoptosis in colon carcinoma cells through transcriptional suppression of the Bcl-xL protein

Bhonde, Mandar R, Hanski, Marie-Luise, Magrini, Roberta, Moorthy, Dhatchana, Müller, Antje, Sausville, Edward A, Kohno, Kimitoshi, Wiegand, Peter, Daniel, Peter T, Zeitz, Martin

Journal:

Year:

2004

Language:

english

File:

PDF, 372 KB

english, 2004

44

Novel small molecule inhibitors of botulinum neurotoxin A metalloprotease activity

James C Burnett, James J Schmidt, Robert G Stafford, Rekha G Panchal, Tam L Nguyen, Ann R Hermone, Jonathan L Vennerstrom, Connor F McGrath, Douglas J Lane, Edward A Sausville, Daniel W Zaharevitz, Ri

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 383 KB

english, 2003

45

Complexities in the development of cyclin-dependent kinase inhibitor drugs

Edward A. Sausville

Journal:

Trends in Molecular Medicine

Year:

2002

Language:

english

File:

PDF, 63 KB

english, 2002

46

A role for ferrous ion and oxygen in the degradation of DNA by bleomycin

Edward A. Sausville, Jack Peisach, Susan B. Horwitz

Journal:

Biochemical and Biophysical Research Communications

Year:

1976

Language:

english

File:

PDF, 476 KB

english, 1976

47

ESMRMB 2013, 30th Annual Scientific Meeting, Toulouse, France, 3-5 October: EPOS™ Poster / Paper Poster / Clinical Review Poster / Software Exhibits

Papadopoulos, Kyriakos P., Burris, Howard A., Gordon, Michael, Lee, Peter, Sausville, Edward A., Rosen, Peter J., Patnaik, Amita, Cutler, Richard E., Wang, Zhengping, Lee, Susan, Jones, Suzanne F., In

Journal:

Magnetic Resonance Materials in Physics, Biology and Medicine

Year:

2013

Language:

english

File:

PDF, 7.13 MB

english, 2013

48

Cytotoxicities of three rebeccamycin derivatives in the National Cancer Institute screening of 60 human tumor cell lines

Moreau, Pascale, Holbeck, Susan, Prudhomme, Michelle, Sausville, Edward A.

Journal:

Anti-Cancer Drugs

Year:

2005

Language:

english

File:

PDF, 181 KB

english, 2005

49

Flow Cytometric Detection of Neoplastic T Cells in Patients with Mycosis Fungoides Based on Levels of T-Cell Receptor Expression

Kuchnio, Miroslaw, Sausville, Edward A., Jaffe, Elaine S., Greiner, Timothy, Foss, Francine M., McClanahan, Julie, Fukushima, Paula, Stetler-Stevenson, Mary Alice

Journal:

American Journal of Clinical Pathology

Year:

1994

Language:

english

File:

PDF, 457 KB

english, 1994

50

CHARACTERIZATION OF A QUANTITATIVE PCR-BASED ASSAY FOR AGENTS ACTIVE AGAINST HUMAN HERPESVIRUS 8.

Shoemaker, Robert H., Halliday, Susan, Fletcher, Thomas, Buckheit, Robert, Sausville, Edward A.

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

1999

File:

PDF, 813 KB

1999

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